Rescale joins agentic HPC pipeline under Genesis Mission

Key Takeaways

• Rescale has been awarded funding under the Genesis Mission to accelerate scientific discovery and national security
• The Genesis Mission aims to double the productivity of the nation's scientific research within a decade
• Rescale will work with national laboratories to extend agentic AI capabilities into advanced simulation codes
• The Agentic HPC Pipeline Initiative (AHPI) will receive funding as part of a $293 million round supporting national science and technology challenges
• Rescale is the only commercial technology company named in the AHPI consortium

Introduction to the Genesis Mission

The U.S. Department of Energy has launched the Genesis Mission, a national initiative aimed at building the world's most powerful integrated science discovery platform. The mission was established by executive order in November 2025 and directs the Department of Energy to mobilize its 17 national laboratories and roughly 40,000 scientists and engineers to accelerate breakthroughs in energy, scientific discovery, and national security.

The Agentic HPC Pipeline Initiative (AHPI)

The AHPI is a funded partner on the Genesis Mission, which uses agentic AI on the Rescale platform to accelerate the adoption of national lab codes by U.S. industry. The initiative addresses a problem that has limited the reach of federally funded science: the country's national laboratories have spent decades developing some of the world's most advanced engineering simulation codes, but meaningful adoption by U.S. manufacturers has been hindered by the specialized expertise and infrastructure required to operate them.

Comparison of AHPI with Other Initiatives

Rescale's Role in the AHPI

Rescale is the only commercial technology company named in the AHPI consortium, working alongside the three national laboratories to extend agentic AI capabilities into WarpX, LiDO, and Adamantine, simulation codes developed respectively at Lawrence Berkeley, Lawrence Livermore, and Oak Ridge. Rescale's platform will enable the acceleration of scientific discovery and national security by providing a scalable and secure infrastructure for the development and deployment of advanced simulation codes.

Conclusion

The Genesis Mission and the AHPI are significant initiatives that aim to accelerate scientific discovery and national security. With Rescale's participation in the AHPI, the company is well-positioned to contribute to the development of advanced simulation codes and accelerate their adoption by U.S. industry. The funding awarded to the AHPI is a testament to the importance of this initiative and the potential impact it can have on the nation's scientific research and development.

Bottom Line

The Genesis Mission and the AHPI are critical initiatives that can drive significant advancements in scientific discovery and national security. With Rescale's expertise in cloud-based high-performance computing and its participation in the AHPI, the company is poised to play a key role in accelerating the adoption of national lab codes by U.S. industry, ultimately contributing to the mission's goal of doubling the productivity of the nation's scientific research within a decade.